Daryl kind of took over tyrese role in the comic but that's. huge stretch as well
Even for those who have read the comics, they have really veered off course in the TV show. That's part of the fun. It's the same general story line, but a lot of the details - some big details, even - are different.
The story they are on now is a LOT different. I can only make one educated guess based on the comics, so it's not really even a spoiler: