I don't think the point was really OSU vs. ISU in this case. More so the disparity between OSU and OU in first round matches.To me, it looks like something that can just happen with random chance. OSU got 3 more matches (8-5) than ISU. That doesn’t seem outrageous to me. Some teams are bound to get more, and some less. That is how randomness works.
The big takeaway for me is that OSU got bonus and ISU did not.