There's a lot of info out there in news articles, but the main points are that CO state government is going to have to have a long discussion with the DEA on how this will be handled within the state, but on a Federal level. Technically it could be brought to the Supreme Court and repealed, but word is that this won't happen since most politicians want to avoid being the guy who reversed something passed by a popular vote. As far as NCAA, jobs, etc. it is still the right of your employer to disallow drug use, and I'm sure many of them still will. Eventually it will get to Iowa, but it will take time. This is almost exactly what happened during the end of alcohol prohibition - it doesn't happen overnight, but starts somewhere. I think it's an incredible opportunity to spend less fighting it and bring in a ton of tax revenue, and assuming this goes well and people realize it's not a big deal, I think other states will follow suit with the money swing being a huge factor.