Massey has Iowa State ranked 22nd (prior to today, but it shouldn't change too much), and in the Big 12 they're behind the teams they lost to (plus Texas) and ahead of the teams they've beaten (plus Kansas and WV).
So let's stick that 22nd-ranked ISU in the SEC:
SEC EAST
6 Florida
9 Georgia
11 SC
41 Tennessee
44 Missouri
52 Vandy
88 Kentucky
SEC WEST
1 Alabama
7 LSU
13 Texas A&M
20 Mississippi State
34 Mississippi
50 Arkansas
75 Auburn
ISU would probably go 4-3 in the East and 3-4 or 4-3 in the West. Could be one win more with an surprise victory; could be one loss more with an unexpected loss. But in either division, and playing a fair selection of teams from the other division, Iowa State could expect to be about .500, and more likely above .500 then below. The Cyclones' expected number of conference wins would probably be slightly higher in the SEC than the Big 12, although that depends on the exact schedule they'd have this year. (With Mississippi State's schedule this year, we'd probably do exactly what they're doing: run off 7 straight to start the season, lose 3 to the SEC murderers' row, and win their last 2 to go 9-3.)
Now, the Big 10:
LEGENDS
23 Nebraska
27 Michigan
35 MSU
36 Northwestern
60 Iowa
66 Minnesota
12 OSU
32 Wisconsin
49 Penn State
69 Indiana
75 Purdue
118 Illinois
In the Big 10, based purely on Massey, we win every conference game except Ohio State and go to the Rose Bowl. It doesn't matter which division we're in or what schedule we have. I am not kidding.