Positives abound over the alternative.
ISU will really have to step up and get serous about developing strong athletic programs as the schedule will be harder than before. But this is good. With only a few exceptions, you don't find programs gaining serious talent through recruiting and building towards the top level that do not play strong schedules. Nor will you draw as much revenue. So, for ISU, its build real competitive teams or get blown out. And honestly, despite the disruption on the men's teams coaching front over the last few years, I think there is a real commitment to building a seriously competitive winning program.
Playing top tier teams provides the opportunity to hone your talent to a sharper edge and it also makes wins count in rankings. And there are teams of top tier caliber in the Big 12 in MBB and Football. Playing them regularly will provide us either the opportunity to lose badly, or to sharpen us to an edge that we could not easily attain if we were in a MWC or similar.
If ISU's goal is to simply field teams and have a good shot of winning, not to develop teams that are capable or competing admirably on the national stage, then we might be better off in a MWC. But if we want to see high level football and basketball, played with the best, then you need to be an a high level conference - like the Big 12.
And we just came oh so close to having to regularly play and beat Air Force, Wyoming and Utah and try and have those victories count for much in changing our national ranking. (Yawn!)