IMO I think Stanzi can be forced into mistakes and he has a suspect offensive line going into the season. That could be a big problem spot. Iowa now has some questions at the running back spot as well with the vanishing act of their top RB.
On defense there is no doubt that they will have a good D-line. They did lose their best LB and they lost their stud CB who shut down half the field with his presence. Sash & Greenwood won't be able to benefit from him like they did last season and it will show. Their secondary IMO is going to be what causes them trouble this year.
Now if you look at Iowa's schedule you look for teams with great offensive lines that will most likely be able to neutralize their D-Line..... Wisconsin, Ohio State, and to a lessor extent ISU. Remember... ISU's O-line more then held their own last season against the hoks. Now if Arnaud can find a way to throw the ball to his receivers and not the defensive backs then we could give them a run for their money.
The (expected) Wegher loss is unfortunate, but not a big loss. He also was not their top RB. At best he was 1A, 1B, or 1C since none of the 3 had a leg up at this point. It is likely that once Hampton gets going he would end up as the #1 regardless of who is on the roster.
I am also not too worried in the secondary. Sash and Greenwood are very good safeties, and Prater is more than capable of replacing Spievey, but defenses will certainly test him.
Can you name the last time that Iowa had a bad linebacker corps?
My main worry is the offensive line at this point. Stanzi is reasonably elusive, but as we all know has had issues with making throws where you just kind of sit there with an open mouth thinking "WTF?" Future first rounder Reiff will be a great left tackle, but the rest of the line is certainly a question mark. The bright side for the offensive line is that the defense will have to respect the run so they won't be able to blitz frequently. DJK and McNutt will be a great 1/2, but Sandeman is not my ideal 3 WR.
At this point I can't see Iowa as a NC contender. After a few games once we see how the OL gels, and how the new LB's and the new CB do then perhaps that discussion might have some relevance. Right now it's a pipe dream.