I graduated from ISU in 1976 to go into broadcasting. However, those were the days when the big push was on to hire minorities and women in radio and T.V. because they had been shut out of those jobs up until then. So that just never worked out for me. In my late 20's I tried insurance sales with Farm Bureau but I failed miserably. I couldn't take all the rejection. After 4 years of that I took what I knew about insurance and became a claim adjuster which lasted over 30 years. I'm not a risk taker so I always wanted the security of a job with benefits.
My wife however had been a supervisor over the Admin team with a couple of different insurers. Her position was eliminated 3 months before my daughter was born so she just took a couple years off. But then the opportunity came about to buy a staffing agency where she had once worked. She did that for 20 years and retired, selling her business for a substantial profit. So she took that risk and it paid off. But, she is a very good manager and great with people.
Finally, and this is not a career change, but my daughter came out of college a few years ago and could go to work for someone if she chose, but instead she decided to just open her own business from the start at age 22. I was like, "No, no, no, take the safe route, get a job first and ease into your profession. But my wife was all, "You can do it! Go for it!" So 4 years later she is having great success, but again she had great skills, is very organized and detail-oriented.
So I guess the key is to know what your tolerance is for risk, and know if you have the drive and can deal with the problems and challenges that are sure to come up. I made a good living and liked what I did, but I played it safe, which was my choice and I have no regrets.