He'll need to look in to AirBNB to list for rent. VRBO requires a whole house (or condo/townhome).
I rented a similar basement only set up in Dubuque this year thru AirBNB. Worked out great for our 2 nt stay. Same price as a hotel but we got much more room and amenities. Separate bedroom, large family room with ping pong table, pool table, sectional, gas fireplace and a kitchen with everything you'd need. The owners weren't home so I can't speak to the noise level but doubt it'd be much of an issue.
I can't speak to what type of draw he'll get because yes, if given a choice I would prefer the whole house if I'm renting. The Dubuque trip was last minute and selection was limited.