The Chicago Art Institute is one of the best, if not THE best, art museums in the nation. There's a wealth of impressionist and modern art, with several major pieces. There's an entire display of Ancient Greek money and art, medieval weapons, Renaissance art, if the more current stuff isn't your scene.
The Field Museum and the Science & Industry Museum are both incredible, also - the S&I one may be a little more geared toward kids. Similarly, my daughter and I enjoyed the planetarium a lot last week, but the movies were probably for a younger crowd, as were some of the exhibits. My husband and son made it to the aquarium and loved it. The Medieval Torture Museum was a blast, and try to catch a show at the Chicago Theatre.
So, we loved Gino's East best of our deep dish excursions (which was inclusive of Lou Malnati's and Pizzeria Uno). However, the best pizza we had in Chicago was thin crust - Coalfire, up near Wrigley. It was fantastic.
There's such great shopping on the Magnificent Mile - Tiffany & Co is a flagship, make sure to stop by. If Yennifer is working, make sure to have her help you.