I believe that cat is out of the bag on that already and there will be no going back. So how do places like ISU deal with the new reality?
Everything that put us behind the richer ADs will just get amplified. The gap will widen. But that's probably not as disturbing as ESPN creating a Super Conference whose only logical conclusion is a Super League. In ESPN's defense...this seems to be what Americans want. Once we relegated the traditional Bowls and deemphasized the sanctity of the conferences tied to those Bowls; in search of "One True Champion", it was only a matter of time before the rich would feel the need to consolidate.
This isn't going to end well for ISU, but we're not alone. Once NFL Lite gets formed there will be many teams outside that group of 32 Super League teams. Who knows, maybe the resultant CFB programs get reformed back to a structure more like the 1970's. It'd be nice, but it won't be as compelling nationally...and will the process crater a bunch of ADs along the way? I don't know, but I DO get the sense that I PERSONALLY, will lose interest.