ISU has two Quad 1 opportunities left, at BU and home vs KSU. If they lose both of those and don't get a Q1 win at KC, they won't get in as an at-large if the WBB Selection Committee behaves like the MBB Committee.
I think this is true in a normal year. We're not quite in a normal year, though, the bubble is very soft. We'd be definitely at risk, but we would have a decent shot to make it, even without one of those wins. Hopefully it won't end up being an issue!
I've been beating the drum for needing a Q1 win, but it is true that the bubble is really soft right now. Looking at Warren Nolan's data, I see 57 teams that are clearly in, including auto-bids where maybe the team isn't clearly in but the spot is spoken for. That leaves 11 spots for teams that don't yet have a solid NCAA Tournament resume. Some of those might go to mid-major spoilers who win their conference tournament and force the best team in the conference to take an at-large slot (although there aren't many mid-majors with great tournament resumes).
(Note: I generally flagged teams with at least 2 Q1 wins as "clearly in", with exceptions for Colorado and Texas A&M with 2 Q1 wins but bad Q2/Q3/Q4 records.)
Top ranked teams (by NET) that I didn't flag as gimmes:
#11 West Virginia. Crazy that a team that high isn't necessarily a gimme, but they are 0-2 in Q1 and 2-2 in Q2. Of six remaining regular-season games, three are Quad 1 and one is just outside Q1 (home vs #26 Utah), so they'll have plenty of chances to prove they belong.
#21 Baylor. 0-3 Q1, 4-2 Q2. Very similar situation to WVU. They also have three of six remaining in Q1, so they'll also have a chance to prove it.
#24 Florida State. 1-4 Q1, 2-1 Q2. Six games left, and the last three are a Q1 murder's row: @ #25 Georgia Tech, @ #4 Notre Dame, vs. #7 Duke. Again, a good chance to prove they should belong.
#25 Georgia Tech. 1-3 Q1, 5-1 Q2. They are probably in good shape anyway, but they do have three low-level Q1 games remaining to solidify their bid.
#31 Minnesota. 0-4 Q1, 2-2 Q2. They are in a similar situation as ISU. Five games left, two are Q1. And their games are both on the road: @ #15 OSU and @ #20 MSU. They need to pull one of those two out to feel better about their chances.
#33 Creighton. 0-4 Q1, 4-0 Q2. Only Q1 game left is a likely loss @ UConn. But no bad losses means they are probably in good shape.
#38 Iowa State. 0-7 Q1, 3-1 Q2, 6-1 Q3 (thanks, UNI). Two Q1 games left.