All of these games were after the Majors era and were bigger in terms of importance. Trying not to duplicate what has been mentioned- several have
1976 ISU @ #16 Okie State for Orange Bowl Birth L 21-42
1976 ISU vs #9 Nebraska for 1st place in Big 8 with one game to go. W 37-28
1976 ISU vs #3 Oklahoma L 10-24
1977 ISU @ Iowa (rebirth of rivalry 40 plus years in the making. The hype exceeded this game- we just did not have social medial to document it. L 10-12
1977 ISU @ #9 Nebraska W 24-21
1977 ISU @ #6 Oklahoma for 1st place in Big 8 L 16-35
1981 ISU vs Iowa ( first Iowa visit to Ames in over 40 years) W 23-12 This game was at least equal to this years.
2017 TCU and OSU games meant more than this Saturday
2018
@texas[
Looking at your list we have not had the best of luck or whatever with big games esp on the road...GO Cyclones Beat TOE