Technology and natural disasters aside. The biggest trend of concern for our civilization is the rise of Authoritarian Nationalism and anti- Democratic forces around the world.
mMost people take our modern civilization, relative peace and standard of living for granted. But the truth is, we all hit the lottery to be born in this time and place in humanities history. And this is largely due to the leadership of Western Democratic nations since we defeated fascism in World War 2. Now, most veterans of the war are gone and many forget the lessons and horrors of war, and how lucky we are to live in free, democratic nations who mostly work together. That is an extreme rarity in our species timeline.
I consider the fact that we haven’t had another world war, or a nuclear war in 80 years to be one of our species greatest achievements. But it’s a way more fragile world than many realize, and it’s not guaranteed to continue.