To me, at least, a 16 team conference, correctly set up, is superior to a 12-team conference, because a 16-team conference gives you all the benefits of a 12-team conference, yet you get a much greater footprint, power, and revenue generating potential in a 16-team conference. Furthermore, in the old B12, we didn't get a cross-divisional protected rivalry game. What we did get in our 12-team conference was 4 OOC games.
Let's revisit the old B12. As ya'll know, we used to play the other 5 teams in our division, our "core rivals," plus 3 from the other division, totalling 8 conference games and 4 OOC games. There was also a 2-year gap between playing every team in the league because we played the three teams from the opposite division on a home-and-home 2 years in a row.
In a 16-team league set up in 4 pods of 4 teams, you have tremendous flexiblity. You can either play full schedule of 7 conference games with 5 OOC games (which the Domers would love, what with their myriad rivalries). Or, you can have a full schedule of 8 conference games, consisting of a cross-pod "protected rivalry" game every year, a second "rivalry game" with another team every 2 out of 3 years, and still get 4 OOC games.
Properly set up, a 16-team conference gives you 4 annual rivalries, 1 other rival you play twice every 3 years, for a core of 5 conference rivals, and you can play every team in the league every 3 years. A correct setup with 16 teams gives you virtually the same 5-core rivalry you get in a 12-team league, along with the same 8 conference games, 4 OOC, and the same 2-year gap required to play every team in the league. Thus, you get the much greater footprint, power, and revenue production of a 16-team league, but with all the benefits of a 12-team league.
A freshman enters college and his school has played every team in the league by the end of his junior year, with the cycle repeating in his senior year. A 16-team league does not necessarily have to be some unwieldy, impersonal conglomeration if it is well-structured.