Definitely. Part of the plan to visit all the old sites and hangouts (if they still exist!)We have stayed at Best Western in Ames with our lab mix. I think they allow dogs up to 80 pounds but they aren’t going to weigh your golden.
We always try to get an Air BnB with the dog first though.
My brothers were at ISU in your era. One lived in Helser and you could easily see Clyde Williams from his room.
Make sure to spend some time driving around central campus.