Last year was our first, giving it another go this year.
We learned the hard way last year that riding on hybrids without clipless pedals (which are actually the kind where the shoe attaches to the pedal) means you are going to get passed, a lot, by 70 year olds on road bikes.
Also, the worst part for us ended up being the way our wrists felt after consecutive days of only having one hand position option (hybrids generally have the straight mountain-bike like handle bars). They got pretty sore in a bad tingly/numb sensation kind of way.
This year we're sticking wtih the hybrids because we didn't feel like shelling out for road bikes we wouldn't otherwise ride very often. We upgraded to clipless pedals, and have new ergonomic handlebar grips with vertical bars on the ends to add a few more hand positions. Hopefully these upgrades help make for a more enjoyable ride this year.
As others have said, it's not a race. When you hit a long hill, don't try to power your way up, as this is a good way to mess up your knees and cut your ride short. Shift down, take your time, and enjoy the tunes coming off the trailer speaker system being pulled by some stud cruising past you.