We took that route a couple of weeks ago on our way to S. Carolina. Not bad at all, once you get to Paducah Ky. its a nice drive, Nashville is a mess, we have to find a better way of going around the city instead of straight through. The further east you get, the better the drive, Tenn. and N and S Carolina are beautiful states to drive through.
By far the worst drives for us are Iowa to Dallas, Kansas just sucks and N. Oklahoma is not much better, but at least you can fly on the toll road, and Nebraska west to Colorado. Both drives are nothing but prairie, with a town every 50 miles or so.
Ever driven up I 29 through North Dakota?