This seems like the biggest problem with either side wanting to get rid of the series to schedule different opponents.
At best you are going to get a P5 also ran most years. The only schools that annually schedule top tier P5 non-con games are teams like Alabama, Georgia, tOSU, and maybe Oklahoma/Texas.
Neither Iowa or ISU are going to be able to get GREAT home and homes scheduled that often. And neither ISU or "mighty" Iowa have the clout to GET the huge matchups. Nobody at Notre Dame is saying they really need to go to Iowa City and invite the vaunted Hokeyes to South Bend. Same with Alabama. They are throwing Wisconsin a bone because they usually win the B1G West and that series is 6 years out. They might do something similar with a team like Iowa, but it's less likely, and series like that are uncommon for teams like Iowa.
Best case scenario, you schedule one huge home and home or neutral site game with say, Georgia. That's one or two games, likely 5 years out. Congratulations, you gave up a proven money maker in the CyHawk game to get one big matchup every 4 or 5 years. The rest of the years you are going to get, at best, a P5 team in the second tier of their conference. You may get a decent crowd to show up for those games, but it's not going to be as good as the CyHawk crowd, and there's no guaranteeing that whatever team you schedule is going to remain in the second tier of their conference for the next 3 years until you play.
It's a "Be careful what you wish for" scenario. Yes there is some fatigue playing CyHawk every year, and the prospect of playing a big SEC team instead sounds great. But you aren't going to get those teams every year.
